Fig. 2

Serial images of case 2 before and after pars plana vitrectomy (PPV) and after intravitreal C3F8 injection. a Colour fundus photograph illustrating a full-thickness macular hole (MH). b–e Serial optical coherence tomography (OCT) image of the case. b Preoperative OCT revealing an idiopathic full-thickness MH with cystoid changes at the edges. c One week after PPV, OCT indicated non-closure of the MH, with minimal intraretinal cysts still present. d One week after intravitreal gas injection, OCT showed closure of the MH, although some disorganisation of the foveal microstructure persisted. e Three months after the intravitreal gas injection, OCT demonstrated that the macular hole was closed and foveal microstructure had improved