Table 3 The correlation between DONFL, and the ratio of GCC complex/central retinal thickness, visual acuity LogMAR and P1 ratio
With DONFL | Without DONFL | With DONFL vs. Without DONFL | ||||||
|---|---|---|---|---|---|---|---|---|
LS-Means (SE) | Difference of LS-Means (95% CI) | p value | LS-Means (SE) | Difference of LS-Means (95% CI) | p value | Difference of LS-Means (SE; 95% CI) | p value | |
GCC complex/central retinal thickness | ||||||||
Baseline | 0.35 (0.02) | Reference | 0.29 (0.02) | Reference | Reference | |||
1.5 months | 0.27 (0.02) | -0.08 (-0.10 to -0.05) | < 0.0001 | 0.24 (0.01) | -0.04 (-0.07 to -0.02) | 0.0017 | -0.03 (0.02; -0.07 to 0.002) | 0.0633 |
3 months | 0.23 (0.01) | -0.12 (-0.15 to -0.09) | < 0.0001 | 0.25 (0.01) | -0.04 (-0.06 to -0.01) | 0.0088 | -0.09 (0.02; -0.13 to -0.04) | < 0.0001 |
≧ 6 months | 0.25 (0.01) | -0.10 (-0.13 to -0.06) | < 0.0001 | 0.26 (0.01) | -0.03 (-0.06 to -0.001) | 0.0399 | -0.07 (0.02; -0.11 to -0.02) | 0.0045 |
Trend: from baseline to ≧ 6 M | -0.03 (-0.04 to -0.02) | < 0.0001 | -0.01 (-0.02 to 0.001) | 0.0628 | -0.02 (0.01; -0.04 to -0.01) | 0.0009 | ||
VA LogMar | ||||||||
Baseline | 0.69 (0.06) | Reference | 0.84 (0.09) | Reference | Reference | |||
1.5 months | 0.65 (0.07) | -0.04 (-0.13 to 0.05) | 0.3789 | 0.71 (0.09) | -0.13 (-0.33 to 0.07) | 0.2126 | 0.09 (0.11; -0.13 to 0.31) | 0.4262 |
3 months | 0.47 (0.05) | -0.21 (-0.26 to -0.17) | < 0.0001 | 0.35 (0.04) | -0.48 (-0.64 to -0.33) | < 0.0001 | 0.27 (0.08; 0.11 to 0.43) | 0.0010 |
≧ 6 months | 0.26 (0.04) | -0.42 (-0.53 to -0.32) | < 0.0001 | 0.24 (0.04) | -0.60 (-0.78 to -0.42) | < 0.0001 | 0.17 (0.11; -0.04 to 0.38) | 0.1068 |
Trend: from baseline to ≧ 6 M | -0.14 (-0.18 to -0.11) | < 0.0001 | -0.21 (-0.28 to -0.15) | < 0.0001 | 0.07 (0.04; 0.001 to 0.14) | 0.0468 | ||
P1 ratio | ||||||||
Baseline | 3.54 (0.14) | Reference | 2.84 (0.11) | Reference | Reference | |||
1.5 months | 2.87 (0.11) | -0.66 (-0.86 to -0.47) | < 0.0001 | 2.79 (0.12) | -0.05 (-0.27 to 0.17) | 0.6748 | -0.61 (0.15; -0.91 to -0.32) | < 0.0001 |
3 months | 2.84 (0.13) | -0.69 (-0.83 to -0.56) | < 0.0001 | 3.27 (0.21) | 0.43 (0.03 to 0.83) | 0.0339 | -1.12 (0.21; -1.54 to -0.70) | < 0.0001 |
≧ 6 months | 3.10 (0.14) | -0.43 (-0.62 to -0.25) | < 0.0001 | 3.58 (0.17) | 0.74 (0.40 to 1.09) | < 0.0001 | -1.18 (0.20; -1.57 to -0.78) | < 0.0001 |
Trend: from baseline to ≧ 6 M | -0.13 (-0.19 to -0.08) | < 0.0001 | 0.27 (0.15 to 0.39) | < 0.0001 | -0.40 (0.07; -0.54 to -0.27) | < 0.0001 | ||