BMC Ophthalmology

Table 3 Statistical Analysis of Treatment Effects: Post Hoc Comparisons Among Study Groups

From: Quorum-Sensing inhibition by furanone compounds and therapeutic effects on Pseudomonas aeruginosa keratitis rabbit model

P-values
*Group*		SLE Score*	CFU Count**	COX- 2*	SOD- 1*	ROS*
Antibiotic-treated (A)	0.1 mg/mL Furanone (B)	< 0.001	0.008	0.012	0.255	0.881
	0.2 mg/mL Furanone (C)	< 0.001	0.008	0.403	0.318	0.749
	0.3 mg/mL Furanone (D)	< 0.001	0.008	0.010	0.453	0.470
	% 20 DMSO (E)	< 0.001	0.007	0.024	0.706	0.092
	Control (N)	< 0.001	0.006	0.007	0.335	0.028
0.1 mg/mL Furanone (B)	0.2 mg/mL Furanone (C)	0.167	0.841	0.074	0.886	0.865
	0.3 mg/mL Furanone (D)	0.841	0.310	0.944	0.690	0.566
	% 20 DMSO (E)	0.234	0.845	0.763	0.441	0.122
	Control (N)	0.167	0.548	0.807	0.857	0.039
0.2 mg/mL Furanone (C)	0.3 mg/mL Furanone (D)	0.234	0.314	0.064	0.798	0.686
	% 20 DMSO (E)	0.014	0.931	0.131	0.529	0.166
	Control (N)	0.009	0.690	0.045	0.970	0.045
0.3 mg/mL Furanone (D)	% 20 DMSO (E)	0.167	0.310	0.710	0.707	0.318
0.3 mg/mL Furanone (D)	Control (N)	0.117	0.151	0.862	0.827	0.121
% 20 DMSO (E)	Control (N)	0.841	0.811	0.586	0.553	0.563

DMSO dimethyl sulfoxide
^*Post hoc test (LSD)
^**Mann–Whitney U test

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