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Table 1 Demographic and Clinical Characteristics of DED Patients with or without Thyroid Disorders

From: Clinical characteristics of dry eye patients with thyroid disorders: a cross-sectional study

 

With thyroid disorders

(n = 47, 47.5%)

With euthyroidism

(n = 52, 52.5%)

P value

Age (years old)

43.68 ± 13.35

46 ± 13.38

0.391

Gender (male, %)

9 (19.1%)

11 (21.2%)

0.804

With hyperlipemia (n, %)

1 (2.1%)

4 (7.7%)

0.207

With autoimmune diseases (n, %)

22 (46.8%)

16 (30.8%)

0.101

TMH (mm)

0.19(0.16, 0.23)

0.22 (0.18, 0.25)

0.192

NIBUT-first (s)

4.59 (3.25, 6.12)

7.33 (5.47, 9.13)

 < 0.001*

NIBUT-avg (s)

8.13 ± 4.03

9.78 ± 3.89

0.042*

S1T (mm/5 min)

4.00 (1.25, 5.75)

5.00 (2.00, 8.00)

0.154

CFS (0,15)

9 (7,11)

9 (8,11)

0.241

MG dropout ratio (%)

32.99%

(21.08%, 55.39%)

17.2%

(11.2%, 27.1%)

0.001*

TSH level (mIU/L)

1.67(1.12, 2.37)

1.67 (1.23, 2.11)

0.664

T3 level (nmol/L)

1.39 (1.23, 1.49)

1.38 (1.28, 1.49)

0.731

T4 level (nmol/L)

97.58 ± 17.94

98.33 ± 15.47

0.824

FT3 level (pmol/L)

4.16 (3.85,4.40)

4.20 (3.95, 4.39)

0.814

FT4 level (pmol/L)

12.93 ± 1.95

12.90 ± 1.20

0.928

Anti-TPO level (IU/ml)

8.65 (5.63, 20.27)

0.99 (0.54, 2.45)

 < 0.001*

Anti-Tg level (IU/ml)

1.94 (0.89,26.15)

0.82 (0.52, 1.18)

 < 0.001*

  1. Data presented includes median values with interquartile ranges or means ± standard deviations as appropriate. P values indicate statistical significance between the two groups
  2. Abbreviations: TMH Tear meniscus height, NIBUT-first the first noninvasive breakup time, NIBUT-avg the average noninvasive breakup time, S1T Schirmer 1 test, CFS Corneal fluorescein staining, MG Meibomian gland, Anti-TPO Anti-thyroid peroxidase antibody, Anti-Tg Anti-thyroglobulin antibody