Fig. 3

Figures A and B show the fibrosis of the Muller’s muscle. A: Histopathology examination shows atrophic smooth muscle (arrow) replaced in some area with fibrosis ((magnification × 40) (H/E staining)), B: Masson’s trichrome stain shows red staining for muscle fiber and blue staining for fibrotic tissue (magnification × 400). Figures C and D show hypertrophy of the Muller’s muscle. C: Hypertrophic Muller’s muscle consists of undulating bundles of smooth muscle fibers (magnification × 400 (H/E staining)), D: Masson’s trichrome staining shows muscle fibers in red. Collagen fibers are stained blue in the perimysium around the muscle bundles (magnification × 400)