Pregnancy-induced ocular changes: impacts on intraocular pressure, the cornea, and the anterior chamber

BMC Ophthalmology

Table 2 A comparison of mean anterior segment parameter values in the control, and first, second, and third trimester groups

	1st Trimester (n = 30) p^b	2nd Trimester (n = 30) p^b	3rd Trimester (n = 30) p^b	Control (n = 30)	p^a
K1 (D)	43.1 ± 2.46 0.469	43.2 ± 1.74 0.988	43.1 ± 1.44 0.998	43.2 ± 1.54	0.877
K2 (D)	44.3 ± 1.34 0.496	43.9 ± 1.79 0.554	43.8 ± 1.54 0.559	44.2 ± 1.70	0.498
Kmax (D)	44.9 ± 1.27 0.717	44.5 ± 1.94 0.348	44.4 ± 1.65 0.395	45.1 ± 2.25	0.523
CCT (µm)	537 ± 34.5 0.609	525 ± 29.7 0.068	526 ± 33.8 0.113	541 ± 39.7	0.202
TCT (µm)	533 ± 34.9 0.945	521 ± 30.7 0.165	521 ± 34.2 0.182	534 ± 40	0.289
CV (mm³)	60.3 ± 3.38 0.973	58.8 ± 3.25 0.116	58.7 ± 3.61 0.261	60.3 ± 4.06	0.162
ACV (mm³)	173 ± 25.6 0.532	167 ± 30.6 0.180	174 ± 30.0 0.127	177 ± 27.4	0.612
ACD (mm)	2.98 ± 0.215 0.934	2.91 ± 0.311 0.313	2.97 ± 0.289 0.638	2.99 ± 0.328	0.672
ACA (º)	39.4 ± 5.56 0.133	38.3 ± 5.64 0.431	36.9 ± 5.45 0.944	37.1 ± 6.47	0.276

Mean ± standard deviation. A p value less than 0.05 was considered statistically significant. K1, flat keratometry; K2, steep keratometry; Kmax, maximum keratometry; CCT, central corneal thickness; TCT, thinnest corneal thickness; CV, corneal volume; ACV, anterior chamber volume; ACD, anterior chamber depth; ACA, anterior chamber angle. ^aComparison within the groups (One-Way ANOVA, Welch’s test). ^bComparison with the controls (Student’s t test)

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