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  1. The performance of glaucoma diagnostic systems could be conceivably improved by the integration of functional and structural test measurements that provide relevant and complementary information for reaching a...

    Authors: Dimitrios Bizios, Anders Heijl and Boel Bengtsson
    Citation: BMC Ophthalmology 2011 11:20
    Content type: Research article Published on:

  2. Pseudoexfoliation (PXF) is a recognized risk factor for developing cataract, glaucoma and lens dislocation. PXF is also associated with increased risk of complications during cataract surgery due to poor mydri...

    Authors: Tarek A Shazly, Abdelsattar N Farrag, Asmaa Kamel and Ashraf K Al-Hussaini
    Citation: BMC Ophthalmology 2011 11:18
    Content type: Research article Published on:

  6. To investigate the clinical relevance of two different preservative formulations, we compared 1-year incidence rates of additional coding of dry eye, ocular infection, or ocular surface disease (either dry eye...

    Authors: Gail F Schwartz, Sameer Kotak, Jack Mardekian and Joel M Fain
    Citation: BMC Ophthalmology 2011 11:14
    Content type: Research article Published on:

  7. Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular press...

    Authors: Joel M Fain, Sameer Kotak, Jack Mardekian, Jason Bacharach, Deepak P Edward, Steven Rauchman, Teresa Brevetti, Janet L Fox and Cherie Lovelace
    Citation: BMC Ophthalmology 2011 11:13
    Content type: Research article Published on:

  11. Ophthalmic viscosurgical devices (OVDs) are widely used in phacoemulsification cataract surgery to maintain adequate intraocular space, stabilize ocular tissue during the operation and decrease the possible da...

    Authors: Marilita M Moschos, Irini P Chatziralli and Theodoros N Sergentanis
    Citation: BMC Ophthalmology 2011 11:9
    Content type: Research article Published on:

  12. Although in vitro and in vivo laboratory studies have suggested that benzalkonium chloride (BAK) in topical ophthalmic solutions may be detrimental to corneal epithelial cells, multiple short- and long-term cl...

    Authors: Gerard Ryan Jr, Joel M Fain, Cherie Lovelace and Karl M Gelotte
    Citation: BMC Ophthalmology 2011 11:8
    Content type: Research article Published on:

  13. To describe the methodology of the Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study III, an ongoing epidemiological study to estimate the prevalence of Diabetes and Diabetic Ret...

    Authors: Swakshyar Saumya Pal, Rajiv Raman, Suganeswari Ganesan, Chinmaya Sahu and Tarun Sharma
    Citation: BMC Ophthalmology 2011 11:7
    Content type: Study protocol Published on:

  15. Scotopic function is an important marker of many retinal diseases and is increasingly used as an outcome measure in clinical trials, such as those investigating gene therapy for Lebers congenital amaurosis. Sc...

    Authors: Michael D Crossland, Vy A Luong, Gary S Rubin and Fred W Fitzke
    Citation: BMC Ophthalmology 2011 11:5
    Content type: Technical advance Published on:

  16. Pituitary adenoma may present with neuro-ophthalmic manifestations and, typically, rapid tumor expansion is the result of apoplexy. Herein, we present the first case of an isolated sixth cranial nerve palsy as...

    Authors: Norman Saffra, Elizabeth Kaplow, Irina Mikolaenko, Alice Kim, Benjamin Rubin and Jafar Jafar
    Citation: BMC Ophthalmology 2011 11:4
    Content type: Case report Published on:

  17. The observation of cytokeratins (CK's) in mass spectrometry based studies raises the question of whether the identified CK is a true endogenous protein from the sample or simply represents a contaminant. This ...

    Authors: Mikkel Lyngholm, Henrik Vorum, Kim Nielsen, Niels Ehlers and Bent Honoré
    Citation: BMC Ophthalmology 2011 11:3
    Content type: Research article Published on:

  18. Cataract and glaucoma are the major causes of blindness in Nepal. Bhaktapur is one of the three districts of Kathmandu valley which represents a metropolitan city with a predominantly agrarian rural periphery....

    Authors: Suman S Thapa, Rosa VD Berg, Shankar Khanal, Indira Paudyal, Pooja Pandey, Nhukesh Maharjan, Shankha N Twyana, Govinda Paudyal, Reeta Gurung, Sanduk Ruit and Ger HMBV Rens
    Citation: BMC Ophthalmology 2011 11:2
    Content type: Research article Published on:

  19. Excessive wound healing, with scarring of the episcleral tissue or encapsulation of the filtering bleb is the main reason for failure in trabeculectomy. Ranibizumab, an inhibitor of the Vascular Endothelial Gr...

    Authors: Frank Bochmann, Claude Kaufmann, Christoph N Becht, Ivo Guber, Michael Kaiser, Lucas M Bachmann and Michael A Thiel
    Citation: BMC Ophthalmology 2011 11:1
    Content type: Study protocol Published on:

  20. Age-related macular degeneration (AMD) is the leading cause of blindness in Western countries. Numerous risk factors have been reported but the evidence and strength of association is variable. We aimed to ide...

    Authors: Usha Chakravarthy, Tien Y Wong, Astrid Fletcher, Elisabeth Piault, Christopher Evans, Gergana Zlateva, Ronald Buggage, Andreas Pleil and Paul Mitchell
    Citation: BMC Ophthalmology 2010 10:31
    Content type: Research article Published on:

  24. Gap junction channels allow direct metabolically and electrical coupling between adjacent cells in various mammalian tissues. Each channel is composed of 12 protein subunits, termed connexins (Cx). In the mous...

    Authors: Goran Söhl, Antonia Joussen, Norbert Kociok and Klaus Willecke
    Citation: BMC Ophthalmology 2010 10:27
    Content type: Research article Published on:

  25. A European-wide population based case-control study (European rare cancer study) undertaken in nine European countries examined risk factors for uveal melanoma. They found a positive association between cooks ...

    Authors: Andrea Schmidt-Pokrzywniak, Karl-Heinz Jöckel, Anja Marr, Norbert Bornfeld and Andreas Stang
    Citation: BMC Ophthalmology 2010 10:26
    Content type: Research article Published on:

  26. Gene silencing in the retina using RNA interference could open broad possibilities for functional studies of genes in vivo and for therapeutic interventions in eye disorders. Therefore, there is a considerable de...

    Authors: Andrey Turchinovich, Georg Zoidl and Rolf Dermietzel
    Citation: BMC Ophthalmology 2010 10:25
    Content type: Technical advance Published on:

  27. To use a new medium to dynamically visualize serial optical coherence tomography (OCT) scans in order to illustrate and elucidate the pathogenesis of idiopathic macular hole formation, progression, and surgica...

    Authors: Ronald C Gentile, Gennady Landa, Mauricio E Pons, Dean Eliott and Richard B Rosen
    Citation: BMC Ophthalmology 2010 10:24
    Content type: Case report Published on:

  28. To describe, a yet non-documented complication of GDI surgery (glaucoma drainage incision surgery) - anterior to posterior segment migration of Ahmed Glaucoma Valve (AGV) tube.

    Authors: Vishnu S Gupta, Harinder S Sethi, Malvika Gupta, Anuj Mehta, Shivram Singh, Pankaj Yadav and KPS Malik
    Citation: BMC Ophthalmology 2010 10:23
    Content type: Case report Published on:

  29. Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological features including β-amyloid (Aβ) peptide accumulation, oxidative damage, and cell death. The causes of AD and AMD...

    Authors: Bhanu Dasari, Jaya RP Prasanthi, Gurdeep Marwarha, Brij B Singh and Othman Ghribi
    Citation: BMC Ophthalmology 2010 10:22
    Content type: Research article Published on:

  30. Prospective, observational studies that enroll large numbers of patients with few exclusion criteria may better reflect actual ongoing clinical experience than randomized clinical trials. Our purpose was to ob...

    Authors: Oliver Schwenn, Barbara Heckmann, Claudia Guzy and Paul J Miller
    Citation: BMC Ophthalmology 2010 10:21
    Content type: Research article Published on:

  31. Despite growing number of intraocular lens power calculation formulas, there is no evidence that these formulas have good predictive accuracy in pediatric, whose eyes are still undergoing rapid growth and refr...

    Authors: Azlyn-Azwa Jasman, Bakiah Shaharuddin, Raja-Azmi M Noor, Shatriah Ismail, Zulkifli A Ghani and Zunaina Embong
    Citation: BMC Ophthalmology 2010 10:20
    Content type: Research article Published on:

  32. Microvascular complications, including retinopathy and nephropathy are seen with type 1 diabetes. It is unknown whether functional changes in aqueous humor flow or intraocular pressure (IOP) develop in paralle...

    Authors: James T Lane, LuAnn Larson, Shan Fan, Julie A Stoner, Eyal Margalit and Carol B Toris
    Citation: BMC Ophthalmology 2010 10:19
    Content type: Research article Published on:

  35. To describe and compare visual function measures of two groups of school age children (6-14 years of age) attending a specialist eyecare practice in Austria; one group referred to the practice from educational...

    Authors: Wolfgang Dusek, Barbara K Pierscionek and Julie F McClelland
    Citation: BMC Ophthalmology 2010 10:16
    Content type: Research article Published on:

  36. The purpose of this study was to reduce the number of items, create a scoring method and assess the psychometric properties of the Freedom from Glasses Value Scale (FGVS), which measures benefits of freedom fr...

    Authors: Gilles Berdeaux, Juliette Meunier, Benoit Arnould and Muriel Viala-Danten
    Citation: BMC Ophthalmology 2010 10:15
    Content type: Research article Published on:

  39. Although a leading cause of visual impairment and a treatable cause of blindness globally, the pattern of refractive errors in many populations is unknown. This study determined the pattern of refractive ocula...

    Authors: Abdulkabir A Ayanniyi, Francisca N Folorunso and Feyisayo G Adepoju
    Citation: BMC Ophthalmology 2010 10:12
    Content type: Research article Published on:

  40. The mechanism by which vitrectomy improves macular edema in patients with branch retinal vein occlusion remains unclear, although intraocular levels of vascular endothelial growth factor have been suggested to...

    Authors: Hidetaka Noma, Hideharu Funatsu, Tatsuya Mimura, Shuichiro Eguchi and Katsunori Shimada
    Citation: BMC Ophthalmology 2010 10:11
    Content type: Research article Published on:

  41. Given the growing number of ocular hypotensive medications available, it is important to be able to predict a positive response to therapy. The purpose of the present study was to identify predictors of an add...

    Authors: Eric Sellem, Jean François Rouland, Christophe Baudouin, Alain Bron, Philippe Denis, Jean-Philippe Nordmann and Jean Paul Renard
    Citation: BMC Ophthalmology 2010 10:10
    Content type: Research article Published on:

  43. To assess the reliability of the measurements obtained with the PalmScanâ„¢, when compared with another standardized A-mode ultrasound device, and assess the consistency and correlation between the two methods.

    Authors: Raul Velez-Montoya, Eugene Mark Shusterman, Miriam Jessica López-Miranda, Mariana Mayorquin-Ruiz, Guillermo Salcedo-Villanueva, Hugo Quiroz-Mercado and Virgilio Morales-Cantón
    Citation: BMC Ophthalmology 2010 10:8
    Content type: Research article Published on:

  44. Patients' understanding of their condition affect the choice of treatment. The aim of this study is to evaluate patients' understanding and treatment preferences before and after an information session on the ...

    Authors: Albert I Matti, Miriam C Keane, Helen McCarl, Pamela Klaer and Celia S Chen
    Citation: BMC Ophthalmology 2010 10:7
    Content type: Research article Published on:

  46. Prior research has demonstrated that medication persistence (continued acquisition of therapy over time) is far from optimal among patients with glaucoma. The purpose of the present study was to evaluate persi...

    Authors: Gregory Reardon, Gail F Schwartz and Sameer Kotak
    Citation: BMC Ophthalmology 2010 10:5
    Content type: Research article Published on:

  47. Prospective, multicenter, randomized, double-masked trials have shown latanoprost instilled once daily to be at least as effective as and generally superior to timolol administered twice daily and to be as eff...

    Authors: Philippe Denis, Christophe Baudouin, Alain Bron, Jean-Philippe Nordmann, Jean Paul Renard, Jean François Rouland, Eric Sellem and Mourad Amrane
    Citation: BMC Ophthalmology 2010 10:4
    Content type: Research article Published on:

  48. Mutations in COL8A2 gene which encodes the collagen alpha-2 (VIII) chain have been identified in both familial and sporadic cases of Fuchs endothelial corneal dystrophy (FECD). Heterozygous mutations in the SLC4A...

    Authors: Boomiraj Hemadevi, Muthiah Srinivasan, Jambulingam Arunkumar, Namperumalsamy V Prajna and Periasamy Sundaresan
    Citation: BMC Ophthalmology 2010 10:3
    Content type: Research article Published on:

  49. Studies have shown that early detection and treatment of neovascular age-related macular degeneration (NV-AMD) can delay vision loss and blindness. The objective of this study was to evaluate the efficacy/safe...

    Authors: Pamela A Weber, Barbara M Wirostko, Xiao Xu, Thomas F Goss and Gergana Zlateva
    Citation: BMC Ophthalmology 2010 10:2
    Content type: Research article Published on:

  50. The objective of this study was to ascertain the scoring and assess the psychometric properties of the Eye-Drop Satisfaction Questionnaire (EDSQ), a 43-item Patient-Reported Outcome instrument developed to ass...

    Authors: Antoine Regnault, Muriel Viala-Danten, Hélène Gilet and Gilles Berdeaux
    Citation: BMC Ophthalmology 2010 10:1
    Content type: Research article Published on:
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