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  1. This study aims to evaluate the effectiveness and safety of phacoemulsification cataract extraction with intraocular lens implantation (PEI) combined with Goniosynechialysis (GSL), Goni-otomy (GT), and PEI com...

    Authors: Mei Li, Yuanhui Jin and Jiangjian Hu
    Citation: BMC Ophthalmology 2025 25:100
    Content type: Research Published on:

  3. The XEN45 Gel Stent (XGS) is an innovative, minimally invasive glaucoma surgery device, which is typically inserted via an ab-interno method, avoiding conjunctival dissection. With increasing experience, some ...

    Authors: Qi Zhang, Chengshou Zhang, Xin Liu, Min Chen and Kaijun Wang
    Citation: BMC Ophthalmology 2025 25:98
    Content type: Case Report Published on:

  4. Myopia is a prevalent disease influenced by both genetic and environmental factors. This study aims to explore myopia risk factors, including the association between night-time reading habits under low illumin...

    Authors: Leonardo Fernández Irigaray, Rodrigo Torres, Virginia Zanutigh, Carla Lanca, Andrzej Grzybowski and Rafael Iribarren
    Citation: BMC Ophthalmology 2025 25:97
    Content type: Research Published on:

  5. This systematic review assesses the efficacy of single-step transepithelial photorefractive keratectomy (tPRK) in terms of postoperative pain, epithelial healing, postoperative haze and visual acuity. It also ...

    Authors: Sharmeen Akram, Wardah Moazzum and Khadijah Abid
    Citation: BMC Ophthalmology 2025 25:93
    Content type: Systematic Review Published on:

  7. To evaluate the progress in Qatar’s eye care since 2009, focusing on effective cataract surgical and refractive error coverages, leading to enhanced eye health strategies and action plans.

    Authors: Shadi M AlAshwal, Muhammad Rabiu, Ian McCormick, Omar AlQahtani, Samya AlAbdulla, Halla Algadi, Suresh Kokku and Mohammed Hamad Al-Thani
    Citation: BMC Ophthalmology 2025 25:96
    Content type: Research Published on:

  8. We examined the relationship between contrast sensitivity (CS) and visual field stage/severity in patients with open-angle glaucoma (OAG), and correlated CS with Quality of Vision (QOV) scores.

    Authors: Rieko Nakano, Ryoko Igarashi, Tadamichi Akagi, Yuta Sakaue, Ryu Iikawa, Ayako Tazawa, Kinuko Kamada, Mao Arimatsu, Tetsuya Togano and Takeo Fukuchi
    Citation: BMC Ophthalmology 2025 25:95
    Content type: Research Published on:

  9. Congenital cataracts (CC) are one of the leading causes of impaired vision or blindness in children, with approximately 8.3–25% being inherited. The aim of this study is to investigate the mutation spectrum an...

    Authors: Hai-Sen Sun, Teng Huang, Zhe-Xuan Liu, Yi-Tong Xu, Ya-Qi Wang, Ming-Cheng Wang, Shen-Rong Zhang, Jia-Lin Xu, Kai-Yi Zhu, Wen-Kai Huang, Xiu-Feng Huang and Jin Li
    Citation: BMC Ophthalmology 2025 25:94
    Content type: Research Published on:

  11. Nance–Horan syndrome (NHS) is a rare X-linked dominant disorder caused by pathogenic variants in the NHS gene on chromosome Xp22.2-Xp22.13. Clinical manifestations consist of congenital cataracts, along with dysm...

    Authors: Teng Huang, Ya-Nan Liu, Dan-Tong Ding, Qiao Wang, Qiu-Ling Xie, Xue-Chuan Miao, Chuan Qin, Xiu-Feng Huang and Jin Li
    Citation: BMC Ophthalmology 2025 25:92
    Content type: Research Published on:

  13. Fibrosis is the primary cause of failure following glaucoma surgery. Wound healing modulation with 5-fluorouracil and mitomycin-C is routinely employed to reduce ocular fibrosis and improve surgical success ra...

    Authors: Ermioni Panidou-Marschelke, Ekaterina Sokolenko, Carsten Framme and Maximilian Binter
    Citation: BMC Ophthalmology 2025 25:88
    Content type: Case Report Published on:

  15. Morphological changes in the retina are crucial and serve as valuable references in the clinical diagnosis of ophthalmic and cardiovascular diseases. However, the retinal vascular structure is complex, making ...

    Authors: Bing Chu, Jinsong Zhao, Wenqiang Zheng and Zhengyuan Xu
    Citation: BMC Ophthalmology 2025 25:86
    Content type: Research Published on:

  16. To explore the changes of iris-trabecular contact (ITC) and intraocular pressure (IOP) in patients who underwent penetrating keratoplasty (PK) during early postoperative period.

    Authors: Yue Li, Yujin Zhao, Jiaxu Hong and Jianjiang Xu
    Citation: BMC Ophthalmology 2025 25:85
    Content type: Research Published on:

  17. Primary open-angle glaucoma (POAG) leads to elevated intraocular pressure (IOP) and gradual optic nerve damage. In a study by Abushanab et al., high-frequency deep sclerotomy (HFDS) effectively treated patient...

    Authors: Wei-Xiang Wang and Mei-Lan Ko
    Citation: BMC Ophthalmology 2025 25:84
    Content type: Case Report Published on:

  18. To describe the clinical features and outcomes of neurotrophic keratopathy (NK) patients treated with minimally invasive corneal neurotization (MICN).

    Authors: Dongyue Tian, Lixia Lin, Xunxun Lin, Kaichen Zhuo, Shuqia Xu, Zhaowei Zhu, Yuwei Xu, Zhancong Ou, Liangbo Zeng, Nan Lin, Jianjun Gu and Yangbin Xu
    Citation: BMC Ophthalmology 2025 25:83
    Content type: Research Published on:

  19. This study aimed to investigate the self-reported dissatisfaction rates and associated risk factors among patients who underwent cataract surgery using different types of presbyopia-correcting intraocular lens...

    Authors: Woosung Jeon, Chang Ho Yoon, Joo Youn Oh, Hyuk Jin Choi and Mee Kum Kim
    Citation: BMC Ophthalmology 2025 25:82
    Content type: Research Published on:

  20. Digital eyestrain (DES) is a collection of ocular and vision symptoms caused by prolonged use of digital devices that can greatly impact schoolchildren’s daily activities and learning. The main purpose of this...

    Authors: Omar H. Almahmoud, Khitam Mohammad Mahmmod, Suhyla Amine Mohtaseb, Nagham Jamil Totah, Doaa Fahim Abu Nijem and Abdallah Nehad Hammoudeh
    Citation: BMC Ophthalmology 2025 25:81
    Content type: Research Published on:

  21. This pilot study aimed to compare ocular biometric data obtained from Pentacam AXL and IOL Master 700 in patients with keratoconus who underwent intracorneal ring segment (ICRS) implantation.

    Authors: Shahram Bamdad, Amirmohammad Fathian, Mohammad Reza Khalili, Mohammad Mohammadi and Alireza Attar
    Citation: BMC Ophthalmology 2025 25:80
    Content type: Research Published on:

  22. To compare the efficacy of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) in treating postvitrectomy cataracts.

    Authors: Lin Wen, Hao Lian, Yi Liu, Bin Wei, Yan Deng, Jianqi Hu, Ying Wu, Min Zhang, Yaoqin Fan and Li Xu
    Citation: BMC Ophthalmology 2025 25:79
    Content type: Research Published on:

  23. Irreversible blindness is the natural history of untreated glaucoma; however, a significant proportion of those receiving treatment are still blind. This study sought to identify the determinant factors respon...

    Authors: Blessing Hafizetu Nwazulu, Nkiru Nwamaka Kizor-Akaraiwe, Suhanya Okeke, Chukwu Oko, Susan Chioma Udeh and Daniel Chukwuemeka Obi
    Citation: BMC Ophthalmology 2025 25:78
    Content type: Research Published on:

  24. High anisometropia is often accompanied by amblyopia. One percent atropine penalization is an important treatment for anisometropic amblyopia and is as effective as occlusion therapy. On the other hand, 1% atr...

    Authors: Qiu-Jian Zhu, Xiao-Qing Chen, Shi-Chuan Yan, Gen-Fang Ma and Lan-Jun Niu
    Citation: BMC Ophthalmology 2025 25:77
    Content type: Case Report Published on:

  27. Circumscribed choroidal hemangioma (CCH) is a benign vascular hamartoma caused by congenital vascular malformation. And, central serous chorioretinopathy (CSCR) is a chorioretinal disease characterized by pach...

    Authors: Jiajia Yao, Kai Yang, Juncai He and Li Ran
    Citation: BMC Ophthalmology 2025 25:75
    Content type: Case Report Published on:

  28. Pars plana vitrectomy (PPV) is an effective treatment of vitreoretinal diseases, while some studies reported visual field defects after surgery. The aim of this study was to evaluate the protective effects of ...

    Authors: Ting Pan, Cunxin Bian, Yuan Fang, Jingfan Wang, Yidan Xu, Ping Xie and Zizhong Hu
    Citation: BMC Ophthalmology 2025 25:74
    Content type: Research Published on:

  29. Limited population-based data as well as proposed mechanisms of retinal ganglion cell (RGC) loss suggest autoimmune disease may be a risk factor for glaucoma, the leading cause of irreversible blindness worldw...

    Authors: Clara M. Castillejo Becerra, Robert O. Funk, Darrell Kohli, David O. Hodge and Gavin W. Roddy
    Citation: BMC Ophthalmology 2025 25:73
    Content type: Research Published on:

  31. To investigate the long-term safety and efficacy of using keratorefractive lenticule extraction (KLEx)-derived corneal stromal lenticules preserved in nutrient capsules for the treatment of corneal diseases.

    Authors: Zhe Zhang, Yanze Yu, Bingqing Sun, Meng Li, Peijun Yao, Xiaoying Wang, Xingtao Zhou and Jing Zhao
    Citation: BMC Ophthalmology 2025 25:64
    Content type: Research Published on:

  32. This study compared the effectiveness of different ultrawide field fundus imaging systems (Clarus™ 500 and Optos®) in diagnosing diabetic retinopathy (DR).

    Authors: Yaoyao Sun, Xiuju Chen, Zongming Song, Tingting Liu, Ye Tao, Tinglan Lai, Yanru Chen, Minghan Li, Jinfeng Qu and Xiaoxin Li
    Citation: BMC Ophthalmology 2025 25:72
    Content type: Research Published on:

  34. Nodular fasciitis (NF), also known as pseudosarcoma fasciitis, is defined as a benign, self-limiting, vascular, or fibrovascular proliferation. It is commonly found on the trunk and upper extremities. NF is ra...

    Authors: Saad Algarni, Hatim Hassan Najmi, Hend Alsawadi, Bayan Alsaif, Reem Alshammari and Shaikha Aleid
    Citation: BMC Ophthalmology 2025 25:70
    Content type: Case Report Published on:

  35. To investigate the tomographic characteristics of corneas with excessive thickness and to explore their potential impact on the assessment of candidates for refractive surgery.

    Authors: Junjie Yu, Ye Xu, Xiaoying Wang and Yishan Qian
    Citation: BMC Ophthalmology 2025 25:69
    Content type: Research Published on:

  36. Amblyopia is associated with structural differences in ocular biometrics, but existing studies often lack long-term follow-ups. This study compares three-year changes in ocular biometric components in amblyopi...

    Authors: Masoud Khorrami-Nejad, Roqayeh Aliyari, Ali Nouraeinejad, Mohsen Heirani, Mohammad Hassan Emamian, Hassan Hashemi and Akbar Fotouhi
    Citation: BMC Ophthalmology 2025 25:68
    Content type: Research Published on:

  37. Age-related macular degeneration (AMD) is a major cause of vision loss worldwide. This study aimed to assess risk factors for wet AMD by two methods: assessing risk factors measured in the Scottish Heart Healt...

    Authors: Catherine A. Fitton, Madeleine M. R. Quigley and Jill J. F. Belch
    Citation: BMC Ophthalmology 2025 25:67
    Content type: Research Published on:

  39. Brown-McLean Syndrome is a rare clinical condition typically presenting as localized edema involving a 2–3 mm peripheral area of the cornea, which often has undergone intraocular surgery.

    Authors: Qi Wan, Li Chen, Ran Wei, Ying-ping Deng, Ke Ma and Jing Tang
    Citation: BMC Ophthalmology 2025 25:62
    Content type: Case Report Published on:

  40. This study aimed to evaluate the efficacy of a simple intravitreal injection of perfluoropropane (C3F8) in treating unclosed idiopathic macular holes (IMHs) in patients who had previously undergone primary pars p...

    Authors: Zexia Dou, Jindong Han and Shaozhen Zhao
    Citation: BMC Ophthalmology 2025 25:61
    Content type: Research Published on:

  41. Selective laser trabeculoplasty (SLT) is a non-invasive treatment option for glaucoma. It uses a Q-switched Nd: YAG laser. The aim of this study was to evaluate the efficacy of SLT as a treatment option for ey...

    Authors: Ahmed AM Gad, Bahaa-Eldin Hasan Abdulhalim, Amal F Gharib and Amr Mahfouz Mohammed
    Citation: BMC Ophthalmology 2025 25:60
    Content type: Research Published on:

  42. Keratoconus is a common disease in clinical practice, and deep anterior lamellar keratoplasty(DALK) is a conventional treatment for keratoconus, which is effective and not easy to recur after surgery.

    Authors: Peicheng Zhang, Yanchao Wu, Lixiao Ma and Dong Wang
    Citation: BMC Ophthalmology 2025 25:59
    Content type: Case Report Published on:

  43. To explore the potential of crystalline lens decentration and tilt as indicators for screening cataract patients for presbyopia-correcting intraocular lens (IOL) implantation.

    Authors: Yu Zhang, Jiaqing Zhang, Chen Liang, Yifan Xu, Jiaying Wu, Junming Wu, Yifan Zhang, Aixia Jin, Xuhua Tan and Lixia Luo
    Citation: BMC Ophthalmology 2025 25:58
    Content type: Research Published on:

  44. Multifocal intraocular lenses (IOLs) are designed to reduce dependence on spectacles by providing multiple focal points. However, they are associated with photic phenomena such as halos and glare, and may redu...

    Authors: João Marcelo de Almeida Gusmão Lyra, Mariana Silva Gois de Almeida, Lucila de Albuquerque Barbosa Lira, Laís Oliveira dos Santos, Mateus Lins dos Santos and Jorge Artur Peçanha de Miranda Coelho
    Citation: BMC Ophthalmology 2025 25:57
    Content type: Research Published on:

  46. To describe the prevalence and the cumulative 6-year incidence of fundus tessellation in a rural Chinese adult population.

    Authors: Caixia Lin, Jian Wu, Kai Cao, Bingsong Wang, Yuxin Fang, Ohno-Matsui Kyoko, Yunyun Sun, Jie Hao, Lixia Ma, Ye Zhang, Qing Zhang and Ningli Wang
    Citation: BMC Ophthalmology 2025 25:55
    Content type: Research Published on:

  47. To evaluate the associations between anatomical changes and visual outcomes after membrane peeling in eyes with different stages of idiopathic epiretinal membrane (iERM) using optical coherence tomography angi...

    Authors: Juan Li, Fangyuan Cheng, Zhaohui Li and Liang Wang
    Citation: BMC Ophthalmology 2025 25:54
    Content type: Research Published on:

  48. Descemet’s membrane endothelial keratoplasty (DMEK) is a highly effective procedure for corneal endothelial dysfunction; however, once a DMEK graft is deployed, repositioning can be challenging. Therefore, thi...

    Authors: Toshiki Shimizu, Itaru Oyakawa, Daisuke Tomida, Hideaki Yokogawa, Akira Kobayashi, Satoru Yamagami and Takahiko Hayashi
    Citation: BMC Ophthalmology 2025 25:53
    Content type: Research Published on:

  49. The post-operative evaluation of trabeculectomy blebs has traditionally relied on subjective clinical grading systems performed at the slit-lamp. This study explores the use of swept source anterior-segment op...

    Authors: Jeremy C.K. Tan, Matthew Roney, Matteo Posarelli, Abdus Samad Ansari, Mark Batterbury and Neeru A. Vallabh
    Citation: BMC Ophthalmology 2025 25:52
    Content type: Research Published on:

  50. This study aims to investigate the correlation between the development of diabetic retinopathy (DR) and the changes in corneal sub-basal nerve plexus (SNP) and corneal dendritic cells (DCs).

    Authors: Yi Zhou, Xiangchen Li, Suhan Shi, Ziwei Guo, Beibei Shan, Linlin Xu, Yixiao Li and Jianxin Guo
    Citation: BMC Ophthalmology 2025 25:51
    Content type: Research Published on:
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