Articles

Intensive outdoor activity for 1 week increases choroidal thickness in Japanese schoolchildren: a prospective observational study

Outdoor activity is important to prevent myopia progression among schoolchildren, and maintaining the choroidal thickness is important to retard myopia progression. However, no research has reported the effect...

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Efficacy of topical mesenchymal stem cell exosome in Sjögren’s syndrome-related dry eye: a randomized clinical trial

Sjögren’s syndrome (SS) is a chronic inflammatory autoimmune disorder affecting salivary and lacrimal glands, leading to distressing ocular symptoms. Existing therapeutic approaches for SS-associated dry eye s...

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Pregnancy-induced ocular changes: impacts on intraocular pressure, the cornea, and the anterior chamber

This study aims to comprehensively evaluate the trimester-specific effects of pregnancy on intraocular pressure, corneal biomechanics, anterior segment anatomy, and endothelial cell morphology.

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Unveiling the levels and significance of different serpin family proteins in aqueous humor dynamics

Alterations in the constituents of the aqueous humor (AH) are associated with various ocular pathologies, including primary open-angle glaucoma (POAG). AH contains a variety of immunomodulatory molecules, incl...

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New marker for the detection of pre-retinopathy in patients with type 1 diabetes mellitus: systemic immuno-inflammation index

This study aimed to investigate the relationships among urine parameters, systemic inflammation and retinal microvascular changes in patients with type 1 diabetes mellitus (T1DM) without clinical signs of diab...

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Application of intraorbital magnets in the removal of magnetic intraorbital foreign bodies

To explore a new surgical method for treating intraorbital foreign bodies.

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Neurosensory binocular vision after bilateral implantation of an extended depth of focus intraocular lens with micro-monovision: a prospective cohort study

The goal of this study was to evaluate the presbyopia-correcting performance, binocular visual quality and neurosensory binocular vision of bilateral implantation of an extended depth of focus (EDOF) intraocul...

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Assessing the clinical outcomes of a novel EDOF intraocular lens: a functional classification approach

Functional assessment can help identify the true extended depth of focus intraocular lenses (EDOF IOLs) on the market. This study aimed to demonstrate the eligibility of the 877PEY ELON IOL (Medicontur Medical...

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The five-step medial epicanthoplasty: simple and standardized

Epicanthus refers to the longitudinal curved skin folds that cover the medial canthus, which affect aesthetics due to covering the medial canthus angle and lacrimal mound. Various surgical methods exist for co...

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Characteristics and surgical outcomes of pediatric traumatic macular holes

Due to the small number of cases, limited knowledge exists on the surgical outcome of pediatric traumatic macular holes (MHs). This study aims to investigate the characteristics and surgical outcomes of pediat...

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The retrograde suture needle threading technique for in-situ repositioning of dislocated intraocular lenses with eyelets

Rescuing dislocated intraocular lenses (IOLs) with eyelets after scleral suture fixation presents technical challenges and risks of ocular tissue damage. We propose a novel in-situ rescue technique for reposit...

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Inverted U-shaped relationship between HbA1c and diabetic retinopathy in diabetic patients: a cross-sectional study

Diabetic retinopathy (DR) is a leading cause of blindness among adults with diabetes. Glycated hemoglobin A1C (HbA1C) is a critical biomarker for long-term glycemic control and has been closely associated with...

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Effects of intravenous d9-THC on pupillary reaction and pupil size: a prospective, placebo-controlled trial in healthy volunteers not regularly consuming cannabis

This prospective, single-blind, placebo-controlled trial examined the effects of intravenous delta-9-tetrahydrocannabinol (d9-THC) on the pupillary light reflex and pupil size in volunteers not regularly consu...

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Application of SS-OCTA to evaluate the effects of long-term hydroxychloroquine treatment on retinal structure and microcirculation in patients with systemic lupus erythematosus

Systemic lupus erythematosus, Hydroxychloroquine, retinal structure and microcirculation, SS-OCTA.

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Investigation of the influencing factors on subjective evaluation in initial and end-of-day silicone hydrogel contact lens wear

This study aimed to investigate the factors influencing subjective ratings of comfort, vision quality, dryness, and satisfaction at both initial and end-of-day wear among young Asian wearers of silicone hydrog...

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The role of childhood overweight in meibomian gland dysfunction and dry eye disease in Chinese children

To explore the factors causing structural abnormalities of meibomian gland in the pediatric population.

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Muller’s muscle fibrosis is a possible predictive factor in the outcome of Muller’s muscle-conjunctival resection

The purpose of our prospective study is to investigate the histopathology of Muller’s muscle extracted after Muller’s Muscle-Conjunctival Resection (MMCR) and to find the relationship between histopathological...

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Efficacy analysis of microinvasive glaucoma surgery alone or in combination with phacoemulsification in patients with normal tension glaucoma: a systematic review and meta-analysis

To assess the effectiveness of minimally invasive glaucoma surgery (MIGS) as monotherapy, or in combination with phacoemulsification, in the management of normal tension glaucoma (NTG).

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A case of bilateral stellate nonhereditary idiopathic foveomacular retinoschisis with 14-month follow-up: clinical features, OCT findings and treatment outcome

Stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) is a relatively recent and rare classification introduced. Currently, there is no reliable treatment for the disease.

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Contributing factors to short-term intraocular pressure elevation following intravitreal anti-VEGF injections

Short-term intraocular pressure (IOP) elevation is a common complication following intravitreal injection (IVI) of anti-VEGF drugs, potentially posing risks to retinal health. This study aimed to identify key ...

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The clinical characteristics, treatment and prognosis differences between occipital brain tumors with venous flow obstruction and occipital brain tumors without venous flow obstruction

To examine the clinical characteristics and prognosis of occipital tumors that mimic Pseudotumor cerebri (PTC) at presentation due to venous flow obstruction compared to occipital tumors that do not cause veno...

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From post-war reconstruction to the twenty-first century – ophthalmic pathology in Freiburg 1945–2015: review of 39,256 surgical specimens from various topographical regions collected over 71 years at a large German tertiary eye care centre

Ophthalmic pathology at the Eye Center at Medical Center, University of Freiburg, Germany, looks back on a tradition of more than 150 years. Surgical specimens and associated histological diagnoses have been a...

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Endophthalmitis following intravitreal injections at a tertiary center: real-life data on incidence, risk factors, management strategies, and visual outcomes

To investigate the incidence, contributing factors, management, and long-term outcomes of endophthalmitis following intravitreal injections performed in our clinic.

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Treatment of corneoscleral mixed hemangioma by intrastromal lenticule transplantation in a case of xeroderma pigmentosum: a case report

Xeroderma pigmentosum (XP) is a rare autosomal recessive skin disease. The ocular manifestations in XP patients usually include severe photophobia, conjunctivitis, corneal opacification, ocular surface squamou...

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A case report of implantable collamer lens removal with cataract extraction and TECNIS Symfony extended range of vision intraocular lens (ZXR00) implantation

Anterior subcapsular cataract (ASC) is a leading complication of implantable collamer lens (ICL) implantation and a common indication for secondary ICL removal. However, the visual outcomes of combined ICL exp...

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Association between myopia and relative peripheral refraction in children with monocular Tilted disc syndrome

This study aimed to investigate the refractive error and relative peripheral refraction in pediatric patients with monocular tilted disc syndrome.

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Analysis of risk factors for vitreous hemorrhage and recurrent hemorrhage after vitrectomy in patients with diabetic retinopathy

To investigate the risk factors associated with recurrent hemorrhage following vitrectomy surgical intervention for diabetic retinopathy (DR).

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Effect of repeated Low-Level red light therapy on axial length in myopic individuals: predictors for a good response

This study aimed to investigate the effects of Repeated Low-Level Red Light (RLRL) therapy on axial length (AL) in myopic individuals and to identify key predictors for a good response to the treatment, with a...

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Different clinical presentations of persistent placoid maculopathy: a case series

Persistent placoid maculopathy is a rare clinical entity defined as idiopathic bilateral chorioretinopathy. We report four different clinical presentations of this pathology.

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Higher-order aberrations and spherical aberration in various age groups after LASIK and cataract surgery

To evaluate higher order aberrations and spherical aberration in various age groups after corneal and lenticular treatments.

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Correlation among ocular surface changes and systemic hematologic indexes and disease activity in primary Sjögren’s syndrome: a cross-sectional study

To explore the relationship among ocular surface changes, systemic hematologic indexes, and disease activity in primary Sjögren’s syndrome patients.

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The use of contact lenses in patients with prior bleb-forming glaucoma surgery

This study aims to investigate the success of contact lens (CL) wear in patients who have had bleb-forming glaucoma surgeries and to assess the rate of CL related complications.

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Predictive factors for adherence to intravitreal anti-vascular endothelial growth factor therapy in Palestinian patients with diabetic retinopathy, retinal vein occlusion, and age-related macular degeneration: a retrospective cohort study

The burden of retinal vascular and degenerative diseases on patients and healthcare systems can be significant if patients do not complete scheduled intravitreal injections. This study aimed to identify the fa...

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Quantitative analysis of ocular deviation under eye occlusion: a descriptive study using the ORTe EYENAC eye-tracking system

The cover–uncover test is traditionally used in the qualitative assessment of heterotropia and heterophoria, while the alternate prism cover test (APCT) quantifies ocular deviations. However, the APCT is time-...

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Correlation analysis between OCT evaluation and postoperative visual prognosis of patients with age-related macular degeneration complicated with cataract

To explore the correlation between optical coherence tomography (OCT) evaluations and postoperative visual prognosis in individuals with AMD complicated with cataract, and to investigate the clinical applicati...

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Exploring leukocyte differential count ratio profiles as inflammatory biomarkers in diabetic retinopathy: a systematic review and meta-analysis

Diabetic retinopathy (DR) is increasingly prevalent and a major cause of irreversible blindness, particularly in developing countries. Limited access to ophthalmologists often leads to delayed diagnosis, empha...

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A retrospective study of posterior vitreous detachment in patients with non-arteritic anterior ischemic optic neuropathy referred to Rasoul Akram hospital in 2022–2023

Previous studies have provided evidence that non-arterial ischemic optic neuropathy (NAION), vitreous traction, and posterior vitreous detachment (PVD) may be related; However, a detailed description of the pr...

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Intraocular pressure correlation to progressive retinal nerve fiber layer loss in primary open angle glaucoma as measured by standard and modified goldmann applanation tonometers

Characterize the relationship between intraocular pressure (IOP) as measured by standard and modified Goldmann prisms and the progressive loss of retinal nerve fiber layer (RNFL) in a cohort of glaucoma patients.

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Bilateral optic neuropathy in Krukenberg tumor treated with FOLFOX plus nivolumab: a case report

A combination of FOLFOX and nivolumab is a first-line treatment for HER2-negative advanced gastric cancer, significantly improving survival. However, this regimen is associated with potential neurotoxicity. 5-...

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Comparison of choroidal vascularity index in rhegmatogenous retinal detachment: impact of silicone-oil vs. gas tamponade following pars plana vitrectomy

This study aimed to evaluate the impact of silicone oil (SO) and perfluoropropane gas (C3F8) tamponade on the choroidal vascularity index (CVI) in patients undergoing pars plana vitrectomy (PPV) for rhegmatoge...

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Increasing myopic refraction reduces random dot stereopsis in Chinese myopic patients: a cross-sectional study

To investigate the effects of myopic spherical equivalent (SE) on random dot stereopsis and influencing factors in Chinese adults with myopia.

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Increased intraocular pressure as the first presenting sign of Miller Fisher syndrome

Miller Fisher syndrome (MFS) is a rare triad of ophthalmoplegia, ataxia, and areflexia. There have been few reports of acute angle-closure glaucoma induced by MFS in the literature. However, acute elevation of...

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Orbital mesenchymal chondrosarcoma and its specific fusion gene HEY1-NCOA2

Mesenchymal chondrosarcoma (MC) is an uncommon type of malignant soft tissue tumor. The skeleton is the most common site of MC. Extraosseous sarcoma is rare, especially that of the orbit. Fusion gene HEY1–NCOA...

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Evaluating the outcomes of inferonasal ahmed valve implantation using the double scleral tunnel technique in refractory glaucoma

To evaluate the efficacy and safety of inferonasal quadrant (IN) Ahmed Valve implantation (AVI) using the double scleral tunnel technique in patients who had previously failed glaucoma surgery.

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Peripapillary Bruch’s membrane Opening-Minimum Rim Width (BMO-MRW) and microvascular changes in early diabetic retinopathy

To evaluate changes in peripapillary Bruch’s Membrane Opening-Minimum Rim Width (BMO-MRW) and its association with peripapillary microvascular in patients with early diabetic retinopathy (DR).

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Correction: Delayed macular development in preterm infants with spontaneously regressed retinopathy of prematurity

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Risk factors for pupil changes in patients with diabetic retinopathy and cataract after phacoemulsification with intraocular lens implantation

This study aims to identify the risk factors associated with pupillary changes in patients with diabetic retinopathy (DR) and cataract undergoing phacoemulsification with intraocular lens implantation (PHACO +...

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Long-term follow-up of retinal amyloid angiopathy in a large Chinese family with hereditary amyloid transthyretin

Retinal amyloid angiopathy (RAA) is an ocular manifestation of hereditary amyloid transthyretin (hATTR). We aimed to investigate the characteristics of disease progression of RAA in patients with ATTR Gly83Arg...

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Thinning of maximum ciliary body thickness: a potential early indicator for pseudophakic malignant glaucoma in primary angle closure glaucoma

Pseudophakic malignant glaucoma (PMG) is an uncommon but severe postoperative complication that poses a significant threat to vision. Early detection of PMG in patients with primary angle closure glaucoma (PAC...

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